Regulation of nuclear factor-κB in autoimmunity
نویسندگان
چکیده
منابع مشابه
Regulation of nuclear factor-κB in autoimmunity.
Nuclear factor (NF)-κB transcription factors are pivotal regulators of innate and adaptive immune responses, and perturbations of NF-κB signaling contribute to the pathogenesis of immunological disorders. NF-κB is a well-known proinflammatory mediator, and its deregulated activation is associated with the chronic inflammation of autoimmune diseases. Paradoxically, NF-κB plays a crucial role in ...
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ژورنال
عنوان ژورنال: Trends in Immunology
سال: 2013
ISSN: 1471-4906
DOI: 10.1016/j.it.2013.01.004